After standing in as best man for his longtime friend Carl Petersen, Randy Dupree loses his job, becomes a barfly and attaches himself to the newlywed couple almost permanently -- as their houseguest. But the longer Dupree camps out on their couch, the closer he gets to Carl's bride, Molly, leaving the frustrated groom wondering when his pal will be moving out.
Andy Stitzer has a pleasant life with a nice apartment and a job stamping invoices at an electronics store. But at age 40, there's one thing Andy hasn't done, and it's really bothering his sex-obsessed male co-workers: Andy is still a virgin. Determined to help Andy get laid, the guys make it their mission to de-virginize him. But it all seems hopeless until Andy meets small business owner Trish, a single mom.
Susan Murphy (a.k.a. Ginormica) and the Monsters are now working with the US government as special ops. So when an alien presence is detected in Susan's hometown of Modesto, California -- right before Halloween -- the team is dispatched to investigate. Everything appears normal, right down to the jack-o-lanterns peering out from every doorstep and windowsill. But when Halloween arrives, those innocent-looking carved pumpkins reveal themselves for what they really are mutant aliens. The altered pumpkins then start to implement their fiendish plan to take over Earth...
Continuing his "legendary adventures of awesomeness", Po must face two hugely epic, but different threats: one supernatural and the other a little closer to his home.
When the Valley of Peace is threatened, lazy Po the panda discovers his destiny as the "chosen one" and trains to become a kung fu hero, but transforming the unsleek slacker into a brave warrior won't be easy. It's up to Master Shifu and the Furious Five -- Tigress, Crane, Mantis, Viper and Monkey -- to give it a try.
Frank leads a group of supermarket products on a quest to discover the truth about their existence and what really happens when they become chosen to leave the grocery store.
A sorority moves in next door to the home of Mac and Kelly Radner who have a young child. The Radner's enlist their former nemeses from the fraternity to help battle the raucous sisters.
In New York City for their annual tradition of Christmas Eve debauchery, three lifelong best friends set out to find the Holy Grail of Christmas parties since their yearly reunion might be coming to an end.
Lifelong platonic friends Zack and Miri look to solve their respective cash-flow problems by making an adult film together. As the cameras roll, however, the duo begin to sense that they may have more feelings for each other than they previously thought.
While attending a party at James Franco's house, Seth Rogen, Jay Baruchel and many other celebrities are faced with the apocalypse.