A group of people gather in the California desert to watch a "film" set in the late 1990s featuring a sentient, homicidal car tire named Robert. The assembled crowd of onlookers watch as Robert becomes obsessed with a beautiful and mysterious woman and goes on a rampage through a desert town.
Hard-to-crack ex-CIA man, Jack Byrnes and his wife, Dina head for the warmer climes of Florida to meet son-in-law-to-be, Greg Focker's parents. Unlike their happily matched offspring, the future in-laws find themselves in a situation of opposites that definitely do not attract.