When shark conservationist Dr. Misty Calhoun is invited to consult on a top-secret project run by pharmaceutical billionaire Carl Durant, she is shocked to learn that the company is using unpredictable and highly aggressive bull sharks as its test subjects, which soon break loose and cause havoc.
Carl Lucas / Frankenstein has won four of his races and needs to win one more to win his freedom. Before his final race, Lucas and his team, car and all, are transferred to another prison where they will compete in a Death Race in the desert. Also, at the same time, Ceaser runs into a marketer who wants to franchise the Death Race program.