A man with a low IQ has accomplished great things in his life and been present during significant historic events—in each case, far exceeding what anyone imagined he could do. But despite all he has achieved, his one true love eludes him.
When Andrew Sterling, a successful black urbanite writer, buys a vacation home on a resort in New England the police mistake him for a burglar. After surrounding his home with armed men, Chief Tolliver realizes his mistake and to avoid the bad publicity offers a thief in his jail, Amos Odell a deal.
Investigative journalist Eddie Brock attempts a comeback following a scandal, but accidentally becomes the host of Venom, a violent, super powerful alien symbiote. Soon, he must rely on his newfound powers to protect the world from a shadowy organization looking for a symbiote of their own.