A supernatural tale set on death row in a Southern prison, where gentle giant John Coffey possesses the mysterious power to heal people's ailments. When the cellblock's head guard, Paul Edgecomb, recognizes Coffey's miraculous gift, he tries desperately to help stave off the condemned man's execution.
A stranger stumbles into the desert town of Absolution with no memory of his past and a futuristic shackle around his wrist. With the help of mysterious beauty Ella and the iron-fisted Colonel Dolarhyde, he finds himself leading an unlikely posse of cowboys, outlaws, and Apache warriors against a common enemy from beyond this world in an epic showdown for survival.