Finding himself in a new era, and approaching retirement, Indy wrestles with fitting into a world that seems to have outgrown him. But as the tentacles of an all-too-familiar evil return in the form of an old rival, Indy must don his hat and pick up his whip once more to make sure an ancient and powerful artifact doesn't fall into the wrong hands.
The inhabitants of the British Isles have lost their battle against the onslaught of disease, as the deadly rage virus has killed every citizen there. Six months later, a group of Americans dare to set foot on the isles, convinced the danger has come and gone. But it soon becomes all too clear that the scourge continues to live, waiting to pounce on its next victims.
During the U.S.-led occupation of Baghdad in 2003, Chief Warrant Officer Roy Miller and his team of Army inspectors were dispatched to find weapons of mass destruction believed to be stockpiled in the Iraqi desert. Rocketing from one booby-trapped and treacherous site to the next, the men search for deadly chemical agents but stumble instead upon an elaborate cover-up that threatens to invert the purpose of their mission.