In Shirleyville, Vermont, during the sixties, sisters Merricat and Constance, along with their ailing uncle Julian, confined to a wheelchair, live isolated in a big mansion located on the hill overlooking the town, tormented by the memories of a family tragedy occurred six years ago. The arrival of cousin Charles will threaten the fragile equilibrium of their minds, haunted by madness, fear and superstition.
Five medical students, hoping to gain insight into the mystery of what lies beyond the confines of life, embark on a daring and dangerous experiment. By stopping their hearts for short periods of time, each triggers a near-death experience. As the investigation becomes more and more perilous, they are forced to confront the sins of their pasts, as well as contend with the paranormal consequences of trespassing to the other side.
When the daughter of a psychiatrist is kidnapped, he's horrified to discover that the abductors' demand is that he break through to a post traumatic stress disorder suffering young woman who knows a secret..